XRN2 antibody (AA 900-950)

Catalog No. ABIN7454718

This Rabbit Polyclonal antibody specifically detects XRN2 in WB, IHC (fp) and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for XRN2 antibody (AA 900-950) (ABIN7454718)

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Product Details anti-XRN2 Antibody

Binding Specificity: AA 900-950

Purpose: Rabbit anti-XRN2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 900 and 950

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for XRN2

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Alternative Name: XRN2

Background: Background: XRN2 is a 5'-to-3' exoribonuclease involved in 3'-end mRNA processing. XRN2 is important for transcription termination and is responsible for degrading the downstream 3'-end-cleaved RNA. Recent studies show that XRN2 is recruited to 3'-end processing machinery by p54nrb/PSF.

Gene ID: 22803

NCBI Accession: NP_036387

UniProt: Q9H0D6