PHF8 antibody (AA 650-700)

Catalog No. ABIN7454781

This Rabbit Polyclonal antibody specifically detects PHF8 in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for PHF8 antibody (AA 650-700) (ABIN7454781)

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PHF8 Antibody

Binding Specificity: AA 650-700

Purpose: Rabbit anti-PHF8 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 650 and 700

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Alternative Name: PHF8

Background: Background: PHF8 (PHD finger protein 8) is a member of the jumonji family of proteins and contains a jumonji C (JmjC) domain. The JmjC proteins are predicted to be metalloenzymes that play a role a chromatin remodeling and histone demethylation. PHF8 also bears a PHD (plant homeodomain)- type zinc-finger, a domain also found to be involved in chromatin remodeling and transcriptional regulation. Truncating mutations in PHF8 are associated with X-linked mental retardation and cleft lip/cleft palate.

Gene ID: 23133

UniProt: Q9UPP1