CDK2 antibody (AA 248-298)
Quick Overview for CDK2 antibody (AA 248-298) (ABIN7454787)
Target
See all CDK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 248-298
-
Purpose
- Rabbit anti-CDK2 Antibody, Affinity Purified
-
Predicted Reactivity
- Rat,Bovine,Golden hamster
-
Purification
- Affinity Purified
-
Immunogen
- between AA 248 and 298
-
Isotype
- IgG
-
-
-
-
Application Notes
-
IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C
-
Expiry Date
- 12 months
-
-
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
-
Alternative Name
- CDK2
-
Background
- Background: Cyclin-dependent kinase 2 (CDK2) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK2 associates with cyclin E or cyclin A to drive the cell cycle through G1- and S-phase. Substrates of CDK2 include pRb, p53, p27, E2F, Brca1, CDK7, B-Myb, PP1 alpha, RNA Pol II CTD, axin, p220 NPAT, ribonucleotide reductase M2, Myo-D, MARCKS, HsCdc6, and CP110.
-
Gene ID
- 1017
-
NCBI Accession
- NP_001789
-
UniProt
- P24941
-
Pathways
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
-