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beta Catenin antibody (AA 760-781)

The Rabbit Polyclonal anti-beta Catenin antibody has been validated for WB, IP and IHC (fp). It is suitable to detect beta Catenin in samples from Human and Mouse.
Catalog No. ABIN7454800

Quick Overview for beta Catenin antibody (AA 760-781) (ABIN7454800)

Target

See all beta Catenin (CATNB) Antibodies
beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity

  • 388
  • 250
  • 226
  • 31
  • 23
  • 22
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  • 7
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  • 1
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Human, Mouse

Host

  • 284
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  • 4
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Rabbit

Clonality

  • 263
  • 137
  • 2
Polyclonal

Conjugate

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This beta Catenin antibody is un-conjugated

Application

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • Binding Specificity

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    AA 760-781

    Purpose

    Rabbit anti-beta Catenin Antibody, Affinity Purified

    Predicted Reactivity

    Rat,X. laevis,Bovine,Dog

    Purification

    Affinity Purified

    Immunogen

    between AA 760 and 781

    Isotype

    IgG
  • Application Notes

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    Alternative Name

    beta Catenin

    Background

    Background: beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.

    Gene ID

    1499

    NCBI Accession

    NP_001895

    UniProt

    P35222

    Pathways

    Peptide Hormone Metabolism
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