EIF6 antibody (AA 150-200)

Catalog No. ABIN7454892

This Rabbit Polyclonal antibody specifically detects EIF6 in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for EIF6 antibody (AA 150-200) (ABIN7454892)

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-EIF6 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-eIF6 Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EIF6

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Alternative Name: eIF6

Background: Background: Eukaryotic translation initiation factor 6 (eIF6) is insoluble and found both in the nucleus and in the cytoplasm. eIF6 can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.eIF6 binds to the fibronectin type III domains of ITGB4 in hemidesmosomes and may help link ITGB4 to the intermediate filament cytoskeleton [taken from NCBI Entrez Gene (Gene ID: 3692].

Gene ID: 3692

NCBI Accession: NP_852133

UniProt: P56537

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly