PINX1 antibody (AA 225-275)

Catalog No. ABIN7455029

The Rabbit Polyclonal anti-PINX1 antibody (ABIN7455029) specifically detects PINX1 in WB, IP and IHC (fp). The antibody is reactive with Human samples.

Quick Overview for PINX1 antibody (AA 225-275) (ABIN7455029)

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-PINX1 Antibody

Binding Specificity: AA 225-275

Purpose: Rabbit anti-PINX1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PINX1

Background: Background: PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. It inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor [taken from the Universal Protein Resource (UniProt) Q96BK5].

Gene ID: 54984

NCBI Accession: NP_060354

UniProt: Q96BK5