ADCY9 antibody (AA 1303-1353)

Catalog No. ABIN7455037

The Rabbit Polyclonal anti-ADCY9 antibody has been validated for WB, IP and IHC (fp). It is suitable to detect ADCY9 in samples from Human and Mouse.

Quick Overview for ADCY9 antibody (AA 1303-1353) (ABIN7455037)

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY9 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-ADCY9 Antibody

Binding Specificity: AA 1303-1353

Purpose: Rabbit anti-AC9 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1303 and 1353

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ADCY9

Target: ADCY9 (Adenylate Cyclase 9 (ADCY9))

Alternative Name: AC9

Background: Background: Adenylyl cyclase 9 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin [taken from NCBI Entrez Gene (Gene ID: 115)].

Gene ID: 115

NCBI Accession: NP_001107

UniProt: O60503

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma