Adracalin antibody (AA 496-546)

Catalog No. ABIN7455041

The Rabbit Polyclonal anti-Adracalin antibody (ABIN7455041) specifically detects Adracalin in WB, IHC (fp) and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for Adracalin antibody (AA 496-546) (ABIN7455041)

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adracalin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Product Details anti-Adracalin Antibody

Binding Specificity: AA 496-546

Purpose: Rabbit anti-Aladin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 496 and 546

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Adracalin

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Alternative Name: Aladin

Background: Background: Aladin is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. Aladin is part of the nuclear pore complex and is anchored there by NDC1. Defects in the coding gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome [taken from NCBI Entrez Gene (Gene ID: 8086)].

Gene ID: 8086

NCBI Accession: NP_056480

UniProt: Q9NRG9