CLNS1A antibody (AA 187-237)

Catalog No. ABIN7455042

This Rabbit Polyclonal antibody specifically detects CLNS1A in WB, IP and IHC (fp). It exhibits reactivity toward Human and Mouse.

Quick Overview for CLNS1A antibody (AA 187-237) (ABIN7455042)

Target: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLNS1A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-CLNS1A Antibody

Binding Specificity: AA 187-237

Purpose: Rabbit anti-ICLN Antibody, Affinity Purified

Predicted Reactivity: Rat,Dog,Rabbit,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 187 and 237

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CLNS1A

Target: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Alternative Name: ICLN

Background: Background: Chloride channel nucleotide sensitive 1A (ICLN) is a protein that functions in multiple regulatory pathways. ICLN complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization.ICLN is also found associated with the plasma membrane where it functions as a chloride current regulator [taken from NCBI Entrez Gene (Gene ID: 1207)].

Gene ID: 1207

NCBI Accession: NP_001284

UniProt: P54105

Pathways: Ribonucleoprotein Complex Subunit Organization