Recombinant MSH6 antibody (AA 1310-1360)

Catalog No. ABIN7455152

This anti-MSH6 antibody is a Rabbit Monoclonal antibody detecting MSH6 in WB, IHC (fp), FACS, ICC and IP. Suitable for Human.

Quick Overview for Recombinant MSH6 antibody (AA 1310-1360) (ABIN7455152)

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MSH6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR117H

Product Details anti-MSH6 Antibody

Binding Specificity: AA 1310-1360

Purpose: Rabbit anti-MSH6 Recombinant Monoclonal Antibody [BLR117H]

Immunogen: between AA 1310 and 1360 (C-term)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MSH6

Target: MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Alternative Name: MSH6

Background: Background: MSH6 is a component of the DNA mismatch repair (MMR) system that functions to recognize base-base mismatches and framshift mispairs. MSH6 forms a heterodimer with MSH2 and is also part of the BRCA1-associated genome surveillance complex (BASC). Mutations in MSH6 have been linked to endometrial carcinoma.

Gene ID: 2956

NCBI Accession: NP_000170

UniProt: P52701

Pathways: DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response