SOX10 antibody (AA 416-466)

Catalog No. ABIN7455186

This Rabbit Polyclonal antibody specifically detects SOX10 in WB, IHC (fp), IF (p), IP and ICC. It exhibits reactivity toward Human and Mouse.

Quick Overview for SOX10 antibody (AA 416-466) (ABIN7455186)

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX10 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-SOX10 Antibody

Binding Specificity: AA 416-466

Purpose: Rabbit anti-SOX10 Antibody, Affinity Purified

Predicted Reactivity: Rat,X. laevis,X. tropicalis,Chicken,Pig

Purification: Affinity Purified

Immunogen: between AA 416 and 466

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 50-100 μL/mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SOX10

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Alternative Name: SOX10

Background: Background: SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX10 may act as a transcriptional activator after forming a protein complex with other proteins. SOX10 acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development [taken from NCBI Entrez Gene (Gene ID: 6663)].

Gene ID: 6663

UniProt: P56693

Pathways: Chromatin Binding