SOX10 antibody (SRY (Sex Determining Region Y)-Box 10) (AA 147-252)

Details for Product anti-SOX10 Antibody No. ABIN1724912
Antigen
Epitope
AA 147-252
111
13
8
8
7
6
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
219
68
38
7
4
2
2
2
2
1
1
1
1
1
1
Host
Mouse
131
86
8
Clonality (Clone)
Monoclonal ()
Conjugate
This SOX10 antibody is un-conjugated
13
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
177
101
92
58
58
48
38
10
6
3
3
2
1
1
1
1
Options
Immunogen Purified recombinant fragment of human SOX10 (AA 147-252) expressed in E. Coli.
Clone 2E7E8
Isotype IgG1
Purification Purified
Antigen
Alternative Name SOX10 (SOX10 Antibody Abstract)
Background This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. ,
Molecular Weight 49.9 kDa
Gene ID 6663
HGNC 6663
Pathways Chromatin Binding
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 147-252) antibody (ABIN1724912) Immunohistochemical analysis of paraffin-embedded breast cancer tissues using SOX10 m...
Product cited in: Shin, Vincent, Cuda, Xu, Kang, Kim, Taube: "Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses." in: Journal of the American Academy of Dermatology, Vol. 67, Issue 4, pp. 717-26, 2012 (PubMed).

Bannykh, Stolt, Kim, Perry, Wegner: "Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas." in: Journal of neuro-oncology, Vol. 76, Issue 2, pp. 115-27, 2006 (PubMed).