ZCCHC8 antibody (AA 1-50)

Catalog No. ABIN7455232

Product Details anti-ZCCHC8 Antibody

Target: ZCCHC8 (Zinc Finger, CCHC Domain Containing 8 (ZCCHC8))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCCHC8 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-ZCCHC8 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:1,000 - 1:5,000

IHC: 1:2,000 - 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ZCCHC8 antibody A301-806A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ZCCHC8

Target: ZCCHC8 (Zinc Finger, CCHC Domain Containing 8 (ZCCHC8))

Alternative Name: ZCCHC8 (ZCCHC8 Products)

Synonyms: MGC80170 antibody, si:ch211-110p13.1 antibody, 5730565F05Rik antibody, zinc finger CCHC-type containing 8 L homeolog antibody, zinc finger CCHC-type containing 8 antibody, zinc finger, CCHC domain containing 8 antibody, zcchc8.L antibody, ZCCHC8 antibody, zcchc8 antibody, Zcchc8 antibody

Background: Background: ZCCHC8 is a zinc-finger protein that bears a zinc-binding motif composed of a CX2CX4HX4C sequence (where X can be any amino acid). ZCCHC8 also bears a PSP domain, a proline rich domain found in numerous splicesome associated proteins. ZCCHC8 has been identified as a component of the splicesome C complex and as a substrate of glycogen synthase kinase-3. It is suggested to play a role in the processing and metabolism of RNA.

Gene ID: 55596

NCBI Accession: NP_060082

UniProt: Q6NZY4