MADD antibody (AA 1597-1647)

Catalog No. ABIN7455235

The Rabbit Polyclonal anti-MADD antibody is suitable to detect MADD in samples from Human. It has been validated for WB, IF (p), IP and IHC (fp).

Quick Overview for MADD antibody (AA 1597-1647) (ABIN7455235)

Target: MADD (MAP-Kinase Activating Death Domain (MADD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MADD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Product Details anti-MADD Antibody

Binding Specificity: AA 1597-1647

Purpose: Rabbit anti-MADD Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 1597 and 1647

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:500 - 1:2,500

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-MADD antibody A302-143A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MADD

Target: MADD (MAP-Kinase Activating Death Domain (MADD))

Alternative Name: MADD

Background: Background: MAP kinase-activating death domain protein (MADD) is a death domain containing protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activate protein kinase (MAPK) and transduce apoptotic signals. MADD is a multi-pass membrane protein that exists as multiple alternatively spliced forms.

Gene ID: 8567

NCBI Accession: NP_003673

UniProt: Q8WXG6

Pathways: Caspase Cascade in Apoptosis