CCR2 antibody

Catalog No. ABIN7490750

The Rabbit Chimeric anti-CCR2 antibody has been validated for FACS. It is suitable to detect CCR2 in samples from Human.

Quick Overview for CCR2 antibody (ABIN7490750)

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Fragment: Fc fragment

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CCR2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-CCR2 Antibody

Characteristics: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt  1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CCR2

Target: CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))

Alternative Name: CCR2

Background: CC-CKR-2, MCP-1-R, CD192,
Description: The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.

UniProt: P41597

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process