Recombinant Prolactin Receptor antibody

Catalog No. ABIN7490762

The Human Chimeric anti-Prolactin Receptor antibody is suitable to detect Prolactin Receptor in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant Prolactin Receptor antibody (ABIN7490762)

Target: Prolactin Receptor (PRLR)

Antibody Type: Recombinant Antibody

Fragment: Fc fragment

Reactivity: Human

Host: Human, Rabbit

Clonality: Chimeric

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: DMC462

Product Details anti-Prolactin Receptor Antibody

Purpose: Anti-PRLR antibody(DMC462), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background: Prolactin receptor, PRL-R,
Description: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus