IL2RG antibody (Biotin)

Catalog No. ABIN7456623

This Rat Monoclonal antibody specifically detects IL2RG in FACS. It exhibits reactivity toward Mouse.

Quick Overview for IL2RG antibody (Biotin) (ABIN7456623)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2RG antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: 3E12

Product Details anti-IL2RG Antibody (Biotin)

Isotype: IgG2b, kappa

Application Details

Application Notes: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Comment:

Matching Isotype Control: Biotin Rat IgG2b, κ Isotype Control (ABIN7469857)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C. Do not freeze.

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132

Background: Cytokine receptor common subunit gamma,Il2rg,Interleukin-2 receptor subunit gamma,IL-2 receptor subunit gamma,IL-2R subunit gamma,IL-2RG,gammaC,p64,CD132,CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Gene ID: 16186

UniProt: P34902

Pathways: JAK-STAT Signaling, Growth Factor Binding