BLK antibody (AA 231-330) (Biotin)

Catalog No. ABIN719353

This Rabbit Polyclonal antibody specifically detects BLK in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for BLK antibody (AA 231-330) (Biotin) (ABIN719353)

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLK antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BLK Antibody (Biotin)

Binding Specificity: AA 231-330

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BLK/MODY11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BLK

Target: BLK (B Lymphoid Tyrosine Kinase (BLK))

Alternative Name: BLK

Background:

Synonyms: B lymphocyte kinase, B lymphoid tyrosine kinase, Blk, BLK nonreceptor tyrosine kinase, BLK_HUMAN, MODY 11, MODY11, P55 BLK, p55-BLK, Tyrosine kinase B lymphocyte specic, Tyrosine protein kinase, Tyrosine-protein kinase BLK.

Background: Modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.

Gene ID: 640

Pathways: Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling