Perforin 1 antibody (FITC)

Catalog No. ABIN7456927

The Rat Monoclonal anti-Perforin 1 antibody has been validated for ICFC. It is suitable to detect Perforin 1 in samples from Mouse.

Quick Overview for Perforin 1 antibody (FITC) (ABIN7456927)

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Perforin 1 antibody is conjugated to FITC

Application: Intracellular Flow Cytometry (ICFC)

Clone: S16009A

Product Details anti-Perforin 1 Antibody (FITC)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: FITC Rat IgG2a,κ Isotype Control (ABIN7469839)

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Alternative Name: Perforin

Background: Prf1, Pfp, Pfn, Pfn-1,Cytolysin,Lymphocyte pore-forming protein,Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.

UniProt: P10820

Pathways: Apoptosis, Caspase Cascade in Apoptosis