CD161 antibody (PE-Cy5)

Catalog No. ABIN7457300

The PE-Cy5-conjugated Mouse Monoclonal anti-CD161 antibody (Clone HP-3G10) (ABIN7457300) specifically detects CD161 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD161 antibody (PE-Cy5) (ABIN7457300)

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD161 antibody is conjugated to PE-Cy5

Application: Flow Cytometry (FACS)

Clone: HP-3G10

Product Details anti-CD161 Antibody (PE-Cy5)

Isotype: IgG1, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: PE/Cyanine5 Mouse IgG1, κ Isotype Control

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD161

Target: CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))

Alternative Name: CD161

Background: CLEC5B, NKRP1A,NKR-P1A,HNKR-P1a,KLRB1,CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.

Gene ID: 3820

UniProt: Q12918