ADORA1 antibody (PE-Cy7)

Catalog No. ABIN719409

This anti-ADORA1 antibody is a Rabbit Polyclonal antibody detecting ADORA1 in WB. Suitable for Human, Rat, Mouse, Pig, Dog, Cow and Chicken.

Quick Overview for ADORA1 antibody (PE-Cy7) (ABIN719409)

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Reactivity: Human, Rat, Mouse, Pig, Dog, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADORA1 antibody is conjugated to PE-Cy7

Application: Western Blotting (WB)

Product Details anti-ADORA1 Antibody (PE-Cy7)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenosine A1 Receptor

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADORA1

Target: ADORA1 (Adenosine A1 Receptor (ADORA1))

Alternative Name: ADORA1

Background:

Synonyms: RDC7, Adenosine receptor A1, ADORA1

Background: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway.

Molecular Weight: 36kDa

Gene ID: 134

UniProt: P30542

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Synaptic Membrane