CD200 antibody (PE-Cy7)

Catalog No. ABIN7457638

The Rat Monoclonal anti-CD200 antibody has been validated for FACS. It is suitable to detect CD200 in samples from Mouse.

Quick Overview for CD200 antibody (PE-Cy7) (ABIN7457638)

Target: CD200

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD200 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: OX-90

Product Details anti-CD200 Antibody (PE-Cy7)

Isotype: IgG2a, kappa

Application Details

Application Notes: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Comment:

Matching Isotype Control: PE/Cyanine7 Rat IgG2a, κ Isotype Control (ABIN7469844)

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD200

Target: CD200

Alternative Name: CD200

Background: OX-2 membrane glycoprotein,OX-2, MRC,CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons), but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.

Gene ID: 4345

UniProt: O54901