Sca-1/Ly-6A/E antibody (PerCP-Cy5.5)
Quick Overview for Sca-1/Ly-6A/E antibody (PerCP-Cy5.5) (ABIN7457826)
Target
See all Sca-1/Ly-6A/E (Ly6a) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG2a, kappa
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Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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Comment
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Matching Isotype Control: PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control (ABIN7469846)
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))
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Alternative Name
- Ly6A/E(Sca-1)
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Background
- Ly6a,Ly6,Ly-6A.2/Ly-6E.1,SCA-1,TAP,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
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Gene ID
- 110454
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UniProt
- P05533
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Pathways
- Sensory Perception of Sound, Activated T Cell Proliferation
Target
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