CD14 antibody (PerCP-Cy5.5)

Catalog No. ABIN7457829

This Mouse Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (PerCP-Cy5.5) (ABIN7457829)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: M5E2

Product Details anti-CD14 Antibody (PerCP-Cy5.5)

Isotype: IgG2a, kappa

Application Details

Application Notes: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Comment:

Matching Isotype Control: PerCP/Cy5.5 Mouse IgG2a, κ Isotype Control (ABIN7469783)

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: Monocyte differentiation antigen CD14,CD14,Myeloid cell-specific leucine-rich glycoprotein,CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.

Gene ID: 929

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades