PEX14 antibody

Catalog No. ABIN7464206

The Rabbit Polyclonal anti-PEX14 antibody (ABIN7464206) specifically detects PEX14 in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for PEX14 antibody (ABIN7464206)

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX14 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: KO Validated

Product Details anti-PEX14 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PEX14. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12 , PC-12 , Rat2

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PEX14

Target: PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))

Alternative Name: peroxisomal biogenesis factor 14

Background: Peroxisomal biogenesis factor 14 , NAPP2 , PBD13A , Pex14p , dJ734G22.2,This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq]

Molecular Weight: 41 kDa

Gene ID: 5195

UniProt: O75381

Pathways: Maintenance of Protein Location