QKI antibody

Catalog No. ABIN7464284

The Mouse Monoclonal anti-QKI antibody (Clone GT2612) (ABIN7464284) specifically detects QKI in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for QKI antibody (ABIN7464284)

Target: QKI (Protein Quaking (QKI))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This QKI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Clone: GT2612

Product Details anti-QKI Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the center region of human QKI. The exact sequence is proprietary.

Isotype: IgG2a

Application Details

Application Notes: WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for QKI

Target: QKI (Protein Quaking (QKI))

Alternative Name: QKI, KH domain containing RNA binding

Background: QKI, KH domain containing RNA binding , Hqk , QK , QK1 , QK3 , hqkI,QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1, MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998 [PubMed 9671495]). QKI proteins regulate RNA splicing, export of target RNAs from the nucleus, translation of proteins, and RNA stability (Lauriat et al., 2008 [PubMed 17918747]).[supplied by OMIM]

Molecular Weight: 38 kDa

Gene ID: 9444

UniProt: Q96PU8