Myosin 9 antibody (N-Term)

Catalog No. ABIN7464342

This Mouse Monoclonal antibody specifically detects Myosin 9 in WB, IF, IHC (p), ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for Myosin 9 antibody (N-Term) (ABIN7464342)

Target: Myosin 9 (MYH9)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Grade: KO Validated

Clone: GT218

Product Details anti-Myosin 9 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MYH9. The exact sequence is proprietary.

Isotype: IgG2b

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: myosin heavy chain 9

Background: Myosin heavy chain 9 , BDPLT6 , DFNA17 , EPSTS , FTNS , MATINS , MHA , NMHC-II-A , NMMHC-IIA , NMMHCA,This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq]

Molecular Weight: 227 kDa

Gene ID: 4627

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex