HDAC2 antibody (C-Term)

Catalog No. ABIN7464379

The Rabbit Polyclonal anti-HDAC2 antibody has been validated for WB, IF, IP, IHC (p), ICC and ChIP. It is suitable to detect HDAC2 in samples from Human.

Quick Overview for HDAC2 antibody (C-Term) (ABIN7464379)

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Chromatin Immunoprecipitation (ChIP)

Grade: KO Validated

Product Details anti-HDAC2 Antibody

Binding Specificity: C-Term

Specificity: Knockdown/Knockout validation was supported by customer review data.

Cross-Reactivity: Human, Mouse, Rat, Xenopus tropicalis

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HDAC2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: C2C12 , Rat2

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.16 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Alternative Name: histone deacetylase 2

Background: Histone deacetylase 2 , HD2 , KDAC2 , RPD3 , YAF1,This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones (H2A, H2B, H3 and H4). This protein also forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus it plays an important role in transcriptional regulation, cell cycle progression and developmental events. [provided by RefSeq]

Molecular Weight: 55 kDa

Gene ID: 3066

UniProt: Q92769

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection