EXOSC5 antibody

Catalog No. ABIN7464455

Product Details anti-EXOSC5 Antibody

Target: EXOSC5 (Exosome Component 5 (EXOSC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human EXOSC5 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , HeLa nuclear extract

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EXOSC5

Target: EXOSC5 (Exosome Component 5 (EXOSC5))

Alternative Name: exosome component 5 (EXOSC5 Products)

Background: Exosome component 5 , RRP41B , RRP46 , Rrp46p , hRrp46p , p12B,Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity.

Molecular Weight: 25 kDa

Gene ID: 56915

UniProt: Q9NQT4

Pathways: SARS-CoV-2 Protein Interactome