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EXOSC5 antibody (AA 1-235) (HRP)

EXOSC5 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7152296
  • Target See all EXOSC5 Antibodies
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Binding Specificity
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    AA 1-235
    Reactivity
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 26
    • 5
    Rabbit
    Clonality
    • 28
    • 3
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC5 antibody is conjugated to HRP
    Application
    • 13
    • 13
    • 11
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Exosome complex component RRP46 protein (1-235AA)
    Isotype
    IgG
    Top Product
    Discover our top product EXOSC5 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Alternative Name
    EXOSC5 (EXOSC5 Products)
    Synonyms
    si:ch211-194n6.2 antibody, zgc:153707 antibody, EXOSC5 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody, hRrp46p antibody, p12B antibody, D7Wsu180e antibody, exosome component 5 antibody, exosc5 antibody, EXOSC5 antibody, Exosc5 antibody
    Background

    Background: Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

    Aliases: Chronic myelogenous leukemia tumor antigen 28 antibody, CML28 antibody, EXOS5_HUMAN antibody, EXOSC 5 antibody, Exosc5 antibody, Exosome complex component rrp46 antibody, exosome complex exonuclease RRP46 antibody, Exosome component 5 antibody, exosome component Rrp46 antibody, hRrp46p antibody, p12B antibody, Ribosomal RNA processing protein 46 antibody, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody, Ribosomal RNA-processing protein 46 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody

    UniProt
    Q9NQT4
    Pathways
    SARS-CoV-2 Protein Interactome
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