FPR2 antibody (N-Term)

Catalog No. ABIN7464596

This anti-FPR2 antibody is a Rabbit Polyclonal antibody detecting FPR2 in WB. Suitable for Human.

Quick Overview for FPR2 antibody (N-Term) (ABIN7464596)

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FPR2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human FPRL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HL-60 membrane extracts

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.95 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: formyl peptide receptor 2

Background: Formyl peptide receptor 2 , ALXR , FMLP-R-II , FMLPX , FPR2A , FPRH1 , FPRH2 , FPRL1 , HM63 , LXA4R,Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Molecular Weight: 39 kDa

Gene ID: 2358

UniProt: P25090