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RNF168 antibody

RNF168 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7464630
  • Target See all RNF168 Antibodies
    RNF168 (Ring Finger Protein 168 (RNF168))
    Reactivity
    • 32
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 27
    • 4
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    This RNF168 antibody is un-conjugated
    Application
    • 28
    • 20
    • 5
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human RNF168. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product RNF168 Primary Antibody
  • Application Notes
    WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: human RNF168-transfected 293T cells , MDA-MB-231 nuclear extract

    Validation: Orthogonal, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RNF168 (Ring Finger Protein 168 (RNF168))
    Alternative Name
    ring finger protein 168 (RNF168 Products)
    Synonyms
    3110001H15Rik antibody, hRNF168 antibody, ring finger protein 168 antibody, ring finger protein 168, E3 ubiquitin protein ligase L homeolog antibody, Rnf168 antibody, rnf168.L antibody, RNF168 antibody
    Background
    Ring finger protein 168 , hRNF168,The complex repair response elicited by DNA double-strand breaks (DSBs) includes recruitment of several DNA repair proteins and ubiquitination of H2A-type histones (see MIM 142720). RNF168 is an E3 ubiquitin ligase critical for DSB repair (Stewart et al., 2009 [PubMed 19203578]).[supplied by OMIM]
    Molecular Weight
    65 kDa
    Gene ID
    165918
    UniProt
    Q8IYW5
    Pathways
    Production of Molecular Mediator of Immune Response
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