Vinexin antibody

Catalog No. ABIN7464648

This Rabbit Polyclonal antibody specifically detects Vinexin in WB, IHC (p), IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Vinexin antibody (ABIN7464648)

Target: Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vinexin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: KO Validated

Product Details anti-Vinexin Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Vinexin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Vinexin

Target: Vinexin (Sorbs3) (Sorbin and SH3 Domain Containing 3 (Sorbs3))

Alternative Name: sorbin and SH3 domain containing 3

Background: Sorbin and SH3 domain containing 3 , SCAM-1 , SCAM1 , SH3D4,The SORBS3 gene encodes 2 isoforms vinexin-alpha and -beta that are vinculin (VCL, MIM 193065)-binding cytoskeletal proteins involved in focal adhesion and cell-cell adhesion (Kioka et al., 1999 [PubMed 9885244]).[supplied by OMIM]

Molecular Weight: 75 kDa

Gene ID: 10174

UniProt: O60504

Pathways: MAPK Signaling