MYL12B antibody

Catalog No. ABIN7464685

Product Details anti-MYL12B Antibody

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL12B antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MRLC2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: K562 , Jurkat , Raji , NCI-H929

Validation: Comparison

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.77 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MYL12B

Target: MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

Alternative Name: myosin light chain 12B (MYL12B Products)

Synonyms: Mrlc2 antibody, Mrlcb antibody, Mylc2b antibody, MLC-B antibody, MRLC2 antibody, 1500001M02Rik antibody, C77744 antibody, RLC-B antibody, MYL12B antibody, mlc-b antibody, mrlc2 antibody, mrlcb antibody, myl12b antibody, myosin light chain 12B antibody, myosin, light chain 12B, regulatory antibody, Myosin regulatory light chain 2 antibody, myosin regulatory light chain 2 antibody, myosin regulatory light chain 12B antibody, myosin light chain 12B L homeolog antibody, Myl12b antibody, MYL12B antibody, mlc-2 antibody, MLC-2 antibody, LOC102175348 antibody, LOC101105123 antibody, LOC100062440 antibody, myl12b.L antibody

Background: Myosin light chain 12B , MLC-B , MRLC2,The activity of nonmuscle myosin II (see MYH9, MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM]

Molecular Weight: 20 kDa

Gene ID: 103910

UniProt: O14950

Pathways: Feeding Behaviour