ARF6 antibody

Catalog No. ABIN7464712

The Rabbit Polyclonal anti-ARF6 antibody has been validated for WB. It is suitable to detect ARF6 in samples from Human.

Quick Overview for ARF6 antibody (ABIN7464712)

Target: ARF6 (ADP-Ribosylation Factor 6 (ARF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARF6 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KO Validated

Product Details anti-ARF6 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ARF6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7 , MDA-MB-231 , mouse brain , rat brain

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.89 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ARF6

Target: ARF6 (ADP-Ribosylation Factor 6 (ARF6))

Alternative Name: ADP ribosylation factor 6

Background: ADP ribosylation factor 6,This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq]

Molecular Weight: 20 kDa

Gene ID: 382

UniProt: P62330

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Actin Filament Polymerization, SARS-CoV-2 Protein Interactome