LTA antibody

Catalog No. ABIN7464926

This anti-LTA antibody is a Rabbit Polyclonal antibody detecting LTA in WB. Suitable for Human.

Quick Overview for LTA antibody (ABIN7464926)

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LTA Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TNF beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: rat spleen , human spleen , LTA-transfected 293T

Validation: Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.08 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: lymphotoxin alpha

Target Type: Chemical

Background: Lymphotoxin alpha , LT , TNFB , TNFSF1 , TNLG1E,Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. [provided by RefSeq]

Molecular Weight: 22 kDa

Gene ID: 4049

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process