PRAM1 antibody (C-Term)

Catalog No. ABIN7464995

The Rabbit Polyclonal anti-PRAM1 antibody (ABIN7464995) specifically detects PRAM1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for PRAM1 antibody (C-Term) (ABIN7464995)

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRAM1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PRAM1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PRAM1

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: PML-RARA regulated adaptor molecule 1

Background: PML-RARA regulated adaptor molecule 1 , PML-RAR , PRAM-1,The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq]

Molecular Weight: 79 kDa

Gene ID: 84106

UniProt: Q96QH2

Pathways: Regulation of Leukocyte Mediated Immunity