MCMBP antibody

Catalog No. ABIN7465088

This anti-MCMBP antibody is a Rabbit Polyclonal antibody detecting MCMBP in WB. Suitable for Human.

Quick Overview for MCMBP antibody (ABIN7465088)

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCMBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MCMBP Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MCMBP. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MCMBP

Target: MCMBP (Minichromosome Maintenance Complex Binding Protein (MCMBP))

Alternative Name: minichromosome maintenance complex binding protein

Background: Minichromosome maintenance complex binding protein , C10orf119 , MCM-BP,DNA replication is a carefully orchestrated process involving many proteins that assemble at origins of replication. Among these are the 6 proteins of the minichromosome maintenance (MCM) complex (e.g., MCM2, MIM 116945), which form a hexamer. Each MCM subunit performs an essential function in initiation and elongation of DNA replication. MCMBP can replace MCM2 in the MCM complex, thus forming an alternative MCM hexamer (Sakwe et al., 2007 [PubMed 17296731]).[supplied by OMIM]

Molecular Weight: 73 kDa

Gene ID: 79892

UniProt: Q9BTE3

Pathways: Chromatin Binding