TRIOBP antibody

Catalog No. ABIN7465234

The Rabbit Polyclonal anti-TRIOBP antibody has been validated for WB, IF, ICC and IHC (p). It is suitable to detect TRIOBP in samples from Human.

Quick Overview for TRIOBP antibody (ABIN7465234)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIOBP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRIOBP Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Tara. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , Rat2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TRIOBP

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: TRIO and F-actin binding protein

Background: TRIO and F-actin binding protein , DFNB28 , HRIHFB2122 , TAP68 , TARA , dJ37E16.4,This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq]

Molecular Weight: 261 kDa

Gene ID: 11078

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization