TNIP2 antibody

Catalog No. ABIN7465459

The Rabbit Polyclonal anti-TNIP2 antibody has been validated for WB, ICC, IF and IHC (p). It is suitable to detect TNIP2 in samples from Human.

Quick Overview for TNIP2 antibody (ABIN7465459)

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TNIP2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Abin 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TNIP2

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Alternative Name: TNFAIP3 interacting protein 2

Background: TNFAIP3 interacting protein 2 , ABIN2 , FLIP1 , KLIP,TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3, MIM 191163) and is involved in activation of the ERK (see MAPK3, MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377], Papoutsopoulou et al., 2006 [PubMed 16633345]).[supplied by OMIM]

Molecular Weight: 49 kDa

Gene ID: 79155

UniProt: Q8NFZ5

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin