TNIP2 antibody (AA 61-110)

Catalog No. ABIN7227160

This Rabbit Polyclonal antibody specifically detects TNIP2 in ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TNIP2 antibody (AA 61-110) (ABIN7227160)

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TNIP2 Antibody

Binding Specificity: AA 61-110

Purpose: Rabbit Anti-Abin-2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Abin-2

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Abin-2 protein at AA range: 61-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TNIP2

Target: TNIP2 (TNFAIP3 Interacting Protein 2 (TNIP2))

Alternative Name: Abin-2

Background: TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting proteinTNIP2 encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to TNIP2 is located on the X chromosome TNIP2 (TNFAIP3 Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Activated TLR4 signalling.

Gene ID: 79155

UniProt: Q8NFZ5

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin