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UNC13D antibody (N-Term)

This anti-UNC13D antibody is a Rabbit Polyclonal antibody detecting UNC13D in WB. Suitable for Human.
Catalog No. ABIN7465484

Quick Overview for UNC13D antibody (N-Term) (ABIN7465484)

Target

See all UNC13D Antibodies
UNC13D (Unc-13 Homolog D (UNC13D))

Reactivity

  • 24
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 20
  • 3
  • 2
Rabbit

Clonality

  • 23
  • 2
Polyclonal

Conjugate

  • 21
  • 2
  • 1
  • 1
This UNC13D antibody is un-conjugated

Application

  • 20
  • 11
  • 8
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)
  • Binding Specificity

    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term

    Cross-Reactivity

    Human, Mouse

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the N-terminus region of human Munc 13-4. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Positive Control: A431 , Mouse lung

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    Preservative

    Thimerosal (Merthiolate)

    Precaution of Use

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    UNC13D (Unc-13 Homolog D (UNC13D))

    Alternative Name

    unc-13 homolog D

    Background

    Unc-13 homolog D , FHL3 , HLH3 , HPLH3 , Munc13-4,This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq]

    Molecular Weight

    123 kDa

    Gene ID

    201294

    UniProt

    Q70J99

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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