PINX1 antibody

Catalog No. ABIN7465528

The Rabbit Polyclonal anti-PINX1 antibody is suitable to detect PINX1 in samples from Human. It has been validated for WB and IP.

Quick Overview for PINX1 antibody (ABIN7465528)

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PINX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-PINX1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PINX1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PIN2 (TERF1) interacting telomerase inhibitor 1

Background: PIN2 (TERF1) interacting telomerase inhibitor 1 , Gno1 , LPTL , LPTS , Pxr1,Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.

Molecular Weight: 37 kDa

Gene ID: 54984

UniProt: Q96BK5