CFHR1 antibody

Catalog No. ABIN7465545

This Rabbit Polyclonal antibody specifically detects CFHR1 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for CFHR1 antibody (ABIN7465545)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CFHR1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CFHL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: complement factor H related 1

Background: Complement factor H related 1 , CFHL , CFHL1 , CFHL1P , CFHR1P , FHR1 , H36-1 , H36-2 , HFL1 , HFL2,This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq]

Molecular Weight: 38 kDa

Gene ID: 3078

UniProt: Q03591