GDF2 antibody (C-Term)

Catalog No. ABIN7465728

This Rabbit Polyclonal antibody specifically detects GDF2 in WB, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for GDF2 antibody (C-Term) (ABIN7465728)

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-GDF2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BMP9. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299 , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Alternative Name: growth differentiation factor 2

Background: Growth differentiation factor 2 , BMP-9 , BMP9 , HHT5,The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq]

Molecular Weight: 47 kDa

Gene ID: 2658

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis