Id2 antibody

Catalog No. ABIN7465742

The Rabbit Polyclonal anti-Id2 antibody (ABIN7465742) specifically detects Id2 in WB, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Id2 antibody (ABIN7465742)

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Id2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Id2 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human ID2 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.82 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Id2

Target: Id2 (Inhibitor of DNA Binding 2 (Id2))

Alternative Name: inhibitor of DNA binding 2

Background: Inhibitor of DNA binding 2 , GIG8 , ID2A , ID2H , bHLHb26,The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene. [provided by RefSeq]

Molecular Weight: 15 kDa

Gene ID: 3398

UniProt: Q02363