NCKIPSD antibody (C-Term)

Catalog No. ABIN7465803

This Rabbit Polyclonal antibody specifically detects NCKIPSD in WB. It exhibits reactivity toward Human.

Quick Overview for NCKIPSD antibody (C-Term) (ABIN7465803)

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKIPSD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCKIPSD Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human NCKIPSD. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116 , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.86 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NCKIPSD

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Alternative Name: NCK interacting protein with SH3 domain

Background: NCK interacting protein with SH3 domain , AF3P21 , DIP , DIP1 , ORF1 , SPIN90 , VIP54 , WASLBP , WISH,The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]

Molecular Weight: 79 kDa

Gene ID: 51517

UniProt: Q9NZQ3

Pathways: Protein targeting to Nucleus