XYLT2 antibody

Catalog No. ABIN7465817

This anti-XYLT2 antibody is a Rabbit Polyclonal antibody detecting XYLT2 in WB, ICC and IF. Suitable for Human.

Quick Overview for XYLT2 antibody (ABIN7465817)

Target: XYLT2 (Xylosyltransferase II (XYLT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XYLT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-XYLT2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Xylosyltransferase II. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for XYLT2

Target: XYLT2 (Xylosyltransferase II (XYLT2))

Alternative Name: xylosyltransferase 2

Background: Xylosyltransferase 2 , PXYLT2 , SOS , XT-II , XT2 , xylT-II,The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. [provided by RefSeq]

Molecular Weight: 97 kDa

Gene ID: 64132

UniProt: Q9H1B5

Pathways: Glycosaminoglycan Metabolic Process