Keratin 6B antibody

Catalog No. ABIN7465818

This Rabbit Polyclonal antibody specifically detects Keratin 6B in WB, IHC (p), IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Keratin 6B antibody (ABIN7465818)

Target: Keratin 6B (KRT6B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 6B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-Keratin 6B Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Cytokeratin 6B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Keratin 6B

Target: Keratin 6B (KRT6B)

Alternative Name: keratin 6B

Background: CK6B antibody , K6B antibody , KRTL1 antibody , PC2 antibody , KRT6B antibody , "keratin , epidermal , type II , K6B antibody" , keratin-6B antibody , cytokeratin-6B antibody , cytokeratin 6B antibody , type-II keratin Kb10 antibody , "keratin , type II cytoskeletal 6B antibody" , keratin-like 1 (a type II keratin sequence) antibody , keratin 6B antibody,The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]

Molecular Weight: 60 kDa

Gene ID: 3854