TRIM24 antibody

Catalog No. ABIN7465861

The Rabbit Polyclonal anti-TRIM24 antibody is suitable to detect TRIM24 in samples from Human. It has been validated for WB.

Quick Overview for TRIM24 antibody (ABIN7465861)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRIM24 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TIF1 alpha. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: tripartite motif containing 24

Background: Tripartite motif containing 24 , PTC6 , RNF82 , TF1A , TIF1 , TIF1A , TIF1ALPHA , hTIF1,The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Molecular Weight: 117 kDa

Gene ID: 8805

UniProt: O15164